Research programme: checkpoint kinase 1 inhibitors - Cascadian/Sentinel

Drug Profile

Research programme: checkpoint kinase 1 inhibitors - Cascadian/Sentinel

Alternative Names: CASC-578; S024; S070; S081; S091; S158; S209

Latest Information Update: 24 Apr 2018

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At a glance

  • Originator Sentinel Oncology
  • Developer Cascadian Therapeutics; Sentinel Oncology
  • Class Small molecules
  • Mechanism of Action Checkpoint kinase 1 inhibitors; DNA repair inhibitors; Phosphotransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 24 Apr 2018 Preclinical development of CASC 578 for Cancer is ongoing in United Kingdom and USA (PO)
  • 28 Mar 2018 No recent reports of development identified for preclinical development in Cancer in United Kingdom (PO)
  • 09 Mar 2018 Cascadian Therapeutics has been acquired by Seattle Genetics
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