Clarithromycin/clofazimine/rifabutin - RedHill Biopharma

Drug Profile

Clarithromycin/clofazimine/rifabutin - RedHill Biopharma

Alternative Names: Clarithromycin/rifabutin/clofazimine; Clofazimine/clarithromycin/rifabutin; Clofazimine/rifabutin/clarithromycin; Myoconda®; RHB 204; RHB-104; Rifabutin/clarithromycin/clofazimine; Rifabutin/clofazimine/clarithromycin

Latest Information Update: 01 Aug 2018

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At a glance

  • Originator Centre for Digestive Diseases
  • Developer RedHill Biopharma
  • Class Anti-inflammatories; Antibacterials; Macrolides; Phenazines; Rifamycins
  • Mechanism of Action Adenosine triphosphatase inhibitors; P-glycoprotein inhibitors; Phospholipase A2 inhibitors; Protein 50S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Crohn's disease
  • New Molecular Entity No

Highest Development Phases

  • Phase III Crohn's disease
  • Phase II Multiple sclerosis
  • Phase I/II Mycobacterial infections
  • Preclinical Psoriasis; Rheumatoid arthritis; Systemic lupus erythematosus
  • No development reported Type 1 diabetes mellitus

Most Recent Events

  • 30 Jul 2018 Topline safety and efficacy results from the MPA US phase III trial in Crohn’s disease released by RedHill Biopharma
  • 28 Jul 2018 No recent reports of development identified for preclinical development in Type-1 diabetes mellitus in Israel (PO, Capsule)
  • 02 Jul 2018 RedHill Biopharma receives Notice of Allowance and Intention to Grant for two patents covering clarithromycin/clofazimine/rifabutin in USA and Europe
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