CRS 3123

Drug Profile

CRS 3123

Alternative Names: CRS3123; REP 3123

Latest Information Update: 25 Jan 2018

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At a glance

  • Originator Replidyne
  • Developer Crestone; National Institute of Allergy and Infectious Diseases
  • Class Antibacterials; Pyridines; Small molecules
  • Mechanism of Action Methionine tRNA ligase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Clostridium-difficile-infections

Most Recent Events

  • 25 Jan 2018 Discontinued - Phase-I for Clostridium difficile infections (In volunteers) in USA (PO)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Clostridium difficile infections(In volunteers) in USA (PO, Capsule)
  • 13 Mar 2014 Crestone and National Institute of Allergy and Infectious Diseases plans a phase I trial (In volunteers) in USA (NCT02106338)
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