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Dexpramipexole - Knopp Biosciences

Drug Profile

Dexpramipexole - Knopp Biosciences

Alternative Names: BIIB 050; KNS-760704; RPPX

Latest Information Update: 07 Sep 2018

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At a glance

  • Originator University of Virginia
  • Developer Biogen Idec; Knopp Biosciences; National Institute of Allergy and Infectious Diseases
  • Class Antiparkinsonians; Benzothiazoles; Neuroprotectants; Small molecules
  • Mechanism of Action Antioxidants; Apoptosis inhibitors; Dopamine receptor agonists; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Amyotrophic lateral sclerosis; Asthma; Hypereosinophilic syndrome

Most Recent Events

  • 05 Sep 2018 Phase-II clinical trials in Asthma in USA (PO)
  • 08 Aug 2018 Knopp Biosciences plans a phase III trial in Hypereosinophilic syndrome
  • 24 Jun 2018 Biomarkers information updated
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