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Opicinumab - Biogen

Drug Profile

Opicinumab - Biogen

Alternative Names: Anti-LINGO 1; Anti-LINGO-1 antibody; BIIB-033

Latest Information Update: 15 Jan 2019

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At a glance

  • Originator Biogen Idec; Dyax
  • Developer Biogen
  • Class Antibodies; Eye disorder therapies; Monoclonal antibodies; Neuroprotectants; Neuropsychotherapeutics
  • Mechanism of Action Cell differentiation stimulants; LINGO 1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Optic neuritis

Most Recent Events

  • 08 Jan 2019 Shire has been acquired and merged into Takeda
  • 30 Sep 2018 Biogen completes enrolment in the phase IIb AFFINITY trial for Multiple sclerosis (Adjunctive treatment) in Australia, Belgium, Canada, Czech Republic, France, Germany, Switzerland, Netherlands, Poland, Spain, Hungary, Italy, United Kingdom (IV) (NCT03222973)
  • 25 Oct 2017 Pharmacodynamics data from a preclinical trial in Optic neuritis presented at the 7th Joint ECTRIMS – ACTRIMS meeting (ECTRIMS – ACTRIMS - 2017)
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