Aclerastide - Derma Sciences

Drug Profile

Aclerastide - Derma Sciences

Alternative Names: [Nle3]-Angiotensin II (1-7); DSC-127; NorLeu3-A(1-7); USB 005

Latest Information Update: 08 Aug 2018

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At a glance

  • Originator University of Southern California
  • Developer Derma Sciences; United States Department of Defense; US Biotest Inc
  • Class Hexanoic acids; Peptides; Skin disorder therapies
  • Mechanism of Action Angiotensin receptor agonists; Stem cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Diabetic foot ulcer

Highest Development Phases

  • Phase I Wounds
  • Suspended Radiation-induced skin damage; Scars
  • Discontinued Diabetic foot ulcer

Most Recent Events

  • 25 Jul 2018 Phase-I clinical trials in Wounds (In volunteers) in USA (Ophthalmic) (NCT03615196)
  • 12 Nov 2015 Discontinued - Phase-III for Diabetic foot ulcer in Canada (Topical)
  • 12 Nov 2015 Discontinued - Phase-III for Diabetic foot ulcer in Puerto Rico (Topical)
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