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Voxtalisib - Exelixis/ Sanofi

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Drug Profile

Voxtalisib - Exelixis/ Sanofi

Alternative Names: SAR-245409; XL-765

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Exelixis
  • Developer EMD Serono; Exelixis; Sanofi
  • Class Antineoplastics; Pyrazoles; Pyridones; Pyrimidines; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Chronic lymphocytic leukaemia; Glioblastoma; HER2 negative breast cancer; Mantle-cell lymphoma; Non-Hodgkin's lymphoma; Ovarian cancer; Solid tumours

Most Recent Events

  • 20 Jan 2021 Discontinued - Phase-I for Chronic lymphocytic leukaemia (Combination therapy) in USA (PO) (Exelixis pipeline, January 2021)
  • 20 Jan 2021 Discontinued - Phase-I for Glioblastoma (Combination therapy) in USA (PO) (Exelixis pipeline, January 2021)
  • 20 Jan 2021 Discontinued - Phase-I for Mantle-cell lymphoma (Combination therapy) in USA (PO) (Exelixis pipeline, January 2021)

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