Voxtalisib - Exelixis/ Sanofi

Drug Profile

Voxtalisib - Exelixis/ Sanofi

Alternative Names: SAR-245409; XL-765

Latest Information Update: 10 Sep 2018

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At a glance

  • Originator Exelixis
  • Developer EMD Serono; Exelixis; Sanofi
  • Class Antineoplastics; Pyrazoles; Pyridones; Pyrimidines; Small molecules
  • Mechanism of Action 1 Phosphatidylinositol 3 kinase inhibitors; MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Chronic lymphocytic leukaemia; Glioblastoma; Mantle-cell lymphoma; Non-Hodgkin's lymphoma; Solid tumours
  • Discontinued Breast cancer; Ovarian cancer

Most Recent Events

  • 10 Sep 2018 Development discontinued for Solid tumours (Combination therapy) in USA and Spain before September 2018 (Sanofi pipeline, September 2018)
  • 10 Sep 2018 Discontinued - Phase-I/II for Solid tumours (Combination therapy) in Belgium, France (PO) (Sanofi pipeline, September 2018)
  • 10 Sep 2018 Discontinued - Phase-I/II for Solid tumours (Monotherapy) in Spain, Belgium, France, USA (PO) (Sanofi pipeline, September 2018)
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