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Olvimulogene nanivacirepvec - Genelux Corporation

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Drug Profile

Olvimulogene nanivacirepvec - Genelux Corporation

Alternative Names: GL-ONC1; GLV-1h68; Olvi-Vec - Genelux Corporation

Latest Information Update: 07 Apr 2025

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At a glance

  • Originator Genelux Corporation
  • Developer Genelux Corporation; Memorial Sloan-Kettering Cancer Center; Newsoara Biopharma
  • Class Antineoplastics; Diagnostic agents; Imaging agents; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Phase II Non-small cell lung cancer
  • Phase I/II Small cell lung cancer
  • No development reported Head and neck cancer; Malignant pleural effusion; Solid tumours

Most Recent Events

  • 25 Mar 2025 Olvi-Vec concludes a productive Type D meeting with the U.S. Food and Drug Administration (FDA) to discuss the requirements necessary for the granting of traditional approval of Olvi-Vec in the treatment of platinum resistant/refractory ovarian cancer
  • 25 Mar 2025 Efficacy and adverse events data from a phase-I/II clinical trials in Small cell lung cancer released by Genelux Corporation
  • 24 Oct 2024 Genelux completes a phase I trial for Malignant pleural effusion in USA (Intrapleural) (NCT01766739)

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