Lirilumab - Bristol-Myers Squibb/Innate Pharma

Drug Profile

Lirilumab - Bristol-Myers Squibb/Innate Pharma

Alternative Names: Anti-KIR (1-7F9); Anti-KIR monoclonal antibody - Innate Pharma; BMS-986015; IPH-21; IPH-2101; IPH-2102; NN 1975; ONO-4483

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Novo Nordisk
  • Developer Bristol-Myers Squibb; Dana-Farber Cancer Institute; Innate Pharma; National Cancer Institute (USA); Ono Pharmaceutical; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action KIR receptor antagonists; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic lymphocytic leukaemia; Head and neck cancer; Myelodysplastic syndromes
  • Phase I/II Solid tumours
  • Phase I Haematological malignancies; Multiple myeloma
  • Preclinical Lymphoma
  • Discontinued Acute myeloid leukaemia; Hepatitis C

Most Recent Events

  • 12 Jul 2018 Bristol-Myers Squibb completes a phase II trial for Acute myeloid leukaemia (Combination therapy) in USA (IV) (NCT02399917)
  • 24 Jun 2018 Biomarkers information updated
  • 22 May 2018 Bristol-Myers Squibb plans a phase I trial for muscle-invasive Bladder Cancer in September 2018 , (NCT03532451)
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