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Pramlintide combination therapy

Drug Profile

Pramlintide combination therapy

Alternative Names: pramlintide + phentermine; pramlintide + PYY3-36; pramlintide + sibutramine; pramlintide/phentermine; pramlintide/PYY3-36; pramlintide/sibutramine

Latest Information Update: 05 Jan 2016

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At a glance

  • Originator Amylin Pharmaceuticals
  • Class Cyclobutanes; Macromolecular substances; Neuropeptides
  • Mechanism of Action Adrenergic receptor antagonists; Dopamine uptake inhibitors; Islet amyloid polypeptide stimulants; Leptin receptor agonists; Neuropeptide Y2 receptor agonists; Neurotransmitter stimulants; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Obesity

Most Recent Events

  • 25 Dec 2012 Amylin Pharmaceuticals and Takeda terminate their agreement for this programme
  • 24 Feb 2010 Discontinued - Phase-II for Obesity in USA (Subcutaneous)
  • 24 Feb 2010 Discontinued - Phase-II for Obesity in USA (Injection/PO combination)
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