KX 01

Drug Profile

KX 01

Alternative Names: KX-2391; KX01

Latest Information Update: 27 Jul 2018

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At a glance

  • Originator Kinex Pharmaceuticals
  • Developer Athenex; Hanmi Pharmaceutical; Kinex Pharmaceuticals; PharmaEssentia Corporation
  • Class Acetamides; Amides; Antineoplastics; Morpholines; Phenyl ethers; Pyridines; Skin disorder therapies; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Interleukin 2 inhibitors; Keratinocyte inhibitors; Src-Family kinase inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Actinic keratosis
  • Phase II Psoriasis
  • Phase I/II Solid tumours
  • No development reported Acute myeloid leukaemia; Prostate cancer

Most Recent Events

  • 26 Jul 2018 Efficacy data from two phase III trial in Actinic keratosis released by Athenex
  • 05 Jul 2018 Athenex plans a phase I trial for Actinic keratosis (Topical) in August 2018 (NCT03575780)
  • 20 Feb 2018 Updated efficacy, adverse events and pharmacokinetics data from a phase II trial in Actinic keratosis released by Athenex
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