KX 01

Drug Profile

KX 01

Alternative Names: KX-2391; KX01

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Kinex Pharmaceuticals
  • Developer Athenex; Hanmi Pharmaceutical; Kinex Pharmaceuticals; PharmaEssentia Corporation
  • Class Acetamides; Amides; Antineoplastics; Antipsoriatics; Morpholines; Phenyl ethers; Pyridines; Skin disorder therapies; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Interleukin 2 inhibitors; Keratinocyte inhibitors; Src-Family kinase inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Actinic keratosis
  • Phase II Psoriasis
  • Phase I/II Solid tumours
  • No development reported Acute myeloid leukaemia; Prostate cancer

Most Recent Events

  • 12 Sep 2018 Athenex will re-acquire the rights to KX 01 oral formulation from Hanmi Pharmaceutical for Korea, China and other Asian territories
  • 14 Aug 2018 Athenex and Almirall plan regulatory submissions for Actinic keratosis
  • 26 Jul 2018 Efficacy data from two phase III trial in Actinic keratosis released by Athenex
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