Auriclosene

Drug Profile

Auriclosene

Alternative Names: AgaDerm; AgaNase; AL-46383A; CD-07223; DCDMT; NVC-422

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator NovaBay Pharmaceuticals
  • Developer Alcon; Galderma; NovaBay Pharmaceuticals
  • Class Alkanesulfonic-acids; Anti-infectives; Antibacterials; Antifungals; Chloramines; Skin disorder therapies; Small molecules
  • Mechanism of Action Protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Catheter infections

Highest Development Phases

  • Phase II/III Impetigo
  • Phase II Catheter infections
  • Preclinical Escherichia coli infections; Klebsiella infections; Onychomycosis
  • No development reported Acne; Staphylococcal infections
  • Discontinued Infectious conjunctivitis; Otorhinolaryngological infections

Most Recent Events

  • 10 Feb 2017 Phase-II development for Catheter infections (Prevention) is ongoing in USA (Instillation, Irrigation)
  • 19 Sep 2016 NovaBay Pharmaceuticals has composition of matter patent protection for Auriclosene in USA up to 2028
  • 19 Sep 2016 Interim adverse events and efficacy data from a phase IIb trial in Catheter infections (Prevention of urinary catheter blockage and encrustation) released by NovaBay Pharmaceuticals
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