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Tofogliflozin - Chugai Pharmaceutical

Drug Profile

Tofogliflozin - Chugai Pharmaceutical

Alternative Names: Apleway; CSG452; Deberza; R 7201; RG 7201; RO4998452; Tofogliflozin hydrate

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Chugai Pharmaceutical
  • Developer Chugai Pharmaceutical; Kowa; Osaka University School of Medicine; Sanofi K.K.
  • Class Antihyperglycaemics; Benzhydryl compounds; Benzofurans; Cardiovascular therapies; Glucosides; Small molecules; Spiro compounds
  • Mechanism of Action Sodium-glucose transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Type 2 diabetes mellitus

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • Phase II Atherosclerosis

Most Recent Events

  • 01 Oct 2018 Efficacy data from pooled analysis of four tofogliflozin phase II and phase III trials in Type 2 diabetes presented at the 54th Annual Meeting of the European Association for the Study of Diabetes (EASD-2018)
  • 24 Jun 2018 Biomarkers information updated
  • 01 Mar 2017 Phase-II clinical trials in Type-2 diabetes mellitus (Adjunctive treatment, Treatment-experienced) in Japan (PO) (UMIN000026161)
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