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TC 6499

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Drug Profile

TC 6499

Alternative Names: TC-6499; TC-6499-12

Latest Information Update: 01 Nov 2023

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At a glance

  • Originator Targacept
  • Developer GlaxoSmithKline; Targacept; Unknown
  • Class Irritable bowel syndrome therapies; Non-opioid analgesics; Small molecules
  • Mechanism of Action Alpha3beta4 nicotinic receptor agonists; Alpha4beta2 nicotinic receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Haematological disorders
  • Discontinued Diabetic gastroparesis; Irritable bowel syndrome; Neuropathic pain

Most Recent Events

  • 30 Oct 2023 GNI has merged with Catalyst Biosciences to form Gyre Therapeutics
  • 29 Nov 2022 No development reported - Phase-II for Haematological disorders (unspecified route)
  • 26 Mar 2018 Phase-I clinical trials in Haematological disorders, prior to March 2018

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