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Vixotrigine - Biogen

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Drug Profile

Vixotrigine - Biogen

Alternative Names: 1014802; BIIB 074; CNV 1014802; CNV 1014802 A; GSK 1014802 A; GSK1014802; Raxatrigine

Latest Information Update: 19 May 2023

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At a glance

  • Originator GlaxoSmithKline
  • Developer Biogen; GlaxoSmithKline
  • Class Analgesics; Neuropsychotherapeutics; Pyrrolidines; Small molecules
  • Mechanism of Action Nav1.7 voltage-gated sodium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Trigeminal neuralgia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Neuropathic pain; Trigeminal neuralgia

Highest Development Phases

  • Discontinued Bipolar disorders; Erythromelalgia; Neuropathic pain; Sciatica; Trigeminal neuralgia

Most Recent Events

  • 06 May 2023 Biogen withdraws phase III trial in Trigeminal neuralgia in Austria (PO) (EudraCT2016-001449-16)
  • 04 May 2023 Biogen withdrawn the phase III SURGE-2 trial in Trigeminal neuralgia (In adults) in Spain, Hungary, Czech Republic (PO) due to sponsor decision (EudraCT2016-002473-35) (NCT03637387)
  • 31 Dec 2022 Discontinued - Phase-I for Trigeminal neuralgia (In volunteers) in USA (PO)

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