Drug Profile


Alternative Names: BMS-820836; DB 104

Latest Information Update: 10 May 2017

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At a glance

  • Originator AMRI
  • Developer Bristol-Myers Squibb; Denovo Biopharma
  • Class Antidepressants; Isoquinolines; Naphthalenes; Pyridazines; Small molecules; Tetrahydroisoquinolines
  • Mechanism of Action Adrenergic receptor antagonists; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Clinical Phase Unknown Depressive disorders
  • Discontinued Major depressive disorder

Most Recent Events

  • 24 Apr 2017 Clinical trials in Depressive disorders in USA (PO)
  • 24 Apr 2017 Denovo Biopharma plans a biomarker driven clinical trial for Depressive disorders
  • 24 Apr 2017 Liafensine licensed to Denovo Biopharma worldwide
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