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Liafensine - Denovo Biopharma

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Drug Profile

Liafensine - Denovo Biopharma

Alternative Names: BMS-820836; DB 104

Latest Information Update: 16 Oct 2024

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At a glance

  • Originator AMRI
  • Developer Bristol-Myers Squibb; Denovo Biopharma
  • Class Antidepressants; Isoquinolines; Naphthalenes; Pyridazines; Small molecules; Tetrahydroisoquinolines
  • Mechanism of Action Adrenergic receptor antagonists; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Depressive disorders
  • Preclinical Major depressive disorder

Most Recent Events

  • 09 Oct 2024 Liafensine - Denovo Biopharma receives Fast Track designation for Depressive disorders [PO] (Treatment-resistant) in USA
  • 03 Apr 2024 Liafensine is available for market licensing
  • 03 Apr 2024 Efficacy and adverse event data from the phase IIb ENLIGHTEN trial in Major depressive disorder released by Denovo Biopharma

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