Apabetalone - Resverlogix

Drug Profile

Apabetalone - Resverlogix

Alternative Names: RVX-000222; RVX-208

Latest Information Update: 11 Jun 2018

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At a glance

  • Originator Resverlogix Corporation
  • Class Anti-inflammatories; Cardiovascular therapies; Quinazolines; Small molecules
  • Mechanism of Action Bromodomain and extraterminal domain protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - HIV infections

Highest Development Phases

  • Phase III Acute coronary syndromes; Atherosclerosis; Low HDL cholesterol
  • Phase II Prediabetic-state
  • Preclinical HIV infections; Renal failure
  • No development reported Alzheimer's disease

Most Recent Events

  • 07 Jun 2018 Apabetalone - Resverlogix is available for licensing as of 07 Jun 2018. www.resverlogix.com
  • 07 Jun 2018 Preclinical trials in HIV infections in Canada before June 2018 (for HIV-1 eradication)
  • 19 Mar 2018 Resverlogix Corporation completes enrolment in the phase III BETonMACE trial in Low HDL cholesterol (PO)
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