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IONIS FXIRx

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Drug Profile

IONIS FXIRx

Alternative Names: BAY-2306001; FXI ASO; ISIS 404071; ISIS-416858; ISIS-FXIRX

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Isis Pharmaceuticals
  • Developer Bayer; Ionis Pharmaceuticals
  • Class Anticoagulants; Antisense oligonucleotides; Antithrombotics
  • Mechanism of Action Factor XI inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Venous thromboembolism
  • Discontinued Thrombosis

Most Recent Events

  • 07 Sep 2021 Discontinued - Phase-I for Thrombosis (Prevention, In volunteers) in USA (SC)
  • 07 Sep 2021 Discontinued - Phase-II for Thrombosis (In the elderly, In adults) in Spain, Austria (SC)
  • 07 Sep 2021 Discontinued - Phase-II for Thrombosis (Prevention) in Canada (SC)

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