Elacestrant - Menarini
Alternative Names: ORSERDU; RAD 1901Latest Information Update: 01 Apr 2026
At a glance
- Originator Eisai Co Ltd
- Developer Menarini; Paratek Pharmaceuticals; Radius Health Inc.; SciClone Pharmaceuticals; Stemline Therapeutics
- Class Amines; Antineoplastics; Ethers; Small molecules; Tetrahydronaphthalenes
- Mechanism of Action Selective estrogen receptor degraders
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed HER2 negative breast cancer
- Discontinued Vasomotor symptoms
Most Recent Events
- 18 Mar 2026 Radius Health Inc. has been acquired and merged into Paratek Pharmaceuticals
- 22 Jul 2025 Clinical trials in HER2-negative-breast-cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT07076680)
- 09 May 2025 Context Therapeutics terminates a phase Ib/II ELONA trial in Breast cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) because sponsor decided to discontinue the development of onapristone (NCT05618613)