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Research programme: kinase inhibitors - Plexxikon

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Drug Profile

Research programme: kinase inhibitors - Plexxikon

Alternative Names: Omni-Raf inhibitors - Plexxikon; PLX-FK1; PLX4720

Latest Information Update: 07 Jul 2022

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At a glance

  • Originator Plexxikon
  • Developer OncoSec Medical; Plexxikon
  • Class Small molecules
  • Mechanism of Action Fms-like tyrosine kinase 3 inhibitors; Macrophage colony-stimulating factor receptor antagonists; Proto-oncogene protein b-raf inhibitors; Proto-oncogene protein b-raf modulators; Raf kinase inhibitors; Vascular endothelial growth factor receptor-1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease; Cancer; Inflammation; Malignant melanoma; Multiple sclerosis; Polycystic kidney disease

Most Recent Events

  • 06 Jul 2022 Discontinued - Preclinical for Alzheimer's disease in USA (PO)
  • 06 Jul 2022 Discontinued - Preclinical for Cancer in USA (PO)
  • 06 Jul 2022 Discontinued - Preclinical for Inflammation in USA (PO)

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