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RG 4733

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RG 4733

Alternative Names: R 4733; RG4733; RO 4929097

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Roche
  • Class Antineoplastics; Benzazepines; Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 19 Nov 2010 Suspended - Phase-II for Non-small cell lung cancer in Netherlands (PO)
  • 08 Jun 2010 Interim efficacy, pharmacodynamics, pharmacokinetics and adverse events data from a phase I trial in Solid tumours presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO-2010)
  • 22 Apr 2009 Pharmacodynamics data from preclinical trials in Solid tumours presented at the 100th Annual Meeting of the American Association for Cancer Research (AACR-2009)

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