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Telomelysin - Oncolys Biopharma

Drug Profile

Telomelysin - Oncolys Biopharma

Alternative Names: OBP-301; Telomelysin; Telomerase-specific Type 5 Adenovirus OBP-301 - Oncolys Biopharma

Latest Information Update: 28 May 2020

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At a glance

  • Originator Oncolys Biopharma
  • Developer Chugai Pharmaceutical; Cornell University; Medigen Biotechnology Corporation; Okayama University; Oncolys BioPharma
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses; Viral proteins
  • Mechanism of Action Cell death stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Gastric cancer; Malignant melanoma; Oesophageal cancer
  • Phase I/II Head and neck cancer; Liver cancer; Non-small cell lung cancer
  • Phase I Solid tumours
  • No development reported Adenoid cystic carcinoma; Breast cancer; Mesothelioma; Neuroblastoma; Osteosarcoma; Skin cancer; Soft tissue sarcoma

Most Recent Events

  • 28 May 2020 No recent reports of development identified for preclinical development in Neuroblastoma in Japan
  • 20 May 2020 National Cancer Institute plans a phase I trial for Oesophageal cancer (Combination therapy, Late-stage disease, Inoperable/Unresectable)in July 2020 (NCT04391049)
  • 23 Apr 2020 Phase-II clinical trials in Oesophageal cancer in Japan (Intratumoural)
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