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MBX 2982

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Drug Profile

MBX 2982

Alternative Names: MBX-2982; SAR-260093

Latest Information Update: 29 Aug 2024

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At a glance

  • Originator Metabolex
  • Developer AdventHealth Translational Research Institute; CymaBay Therapeutics
  • Class Antihyperglycaemics; Benzene derivatives; Ethers; Hepatoprotectants; Piperidines; Pyrimidines; Small molecules; Tetrazoles; Thiazoles
  • Mechanism of Action GPR119 protein agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Liver disorders; Type 1 diabetes mellitus; Type 2 diabetes mellitus

Most Recent Events

  • 21 Jun 2024 Efficacy data from the phase IIa PHROG trial in Type 1 diabetes mellitus presented at the 84th Annual Scientific Sessions of the American Diabetes Association (ADA-2024)
  • 22 Mar 2024 CymaBay Therapeutics has been acquired by Gilead Sciences
  • 07 Nov 2023 Discontinued - Phase-I for Liver disorders in USA (PO)

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