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Prezalumab - Amgen/AstraZeneca

Drug Profile

Prezalumab - Amgen/AstraZeneca

Alternative Names: AMG-557; B7RP-1 mAb; MEDI-5872

Latest Information Update: 06 Nov 2023

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At a glance

  • Originator Amgen
  • Developer Amgen; MedImmune
  • Class Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action B7-related protein 1 inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cutaneous lupus erythematosus; Psoriasis; Sjogren's syndrome; Systemic lupus erythematosus

Most Recent Events

  • 15 Mar 2021 Viela Bio has been acquired and merged into Horizon Therapeutics plc
  • 08 Nov 2019 Adverse events, efficacy and immunogenicity data from a phase II trial in Sjogren's syndrome presented at the 83rd American College of Rheumatology and the 54th Association of Rheumatology Health Professionals Annual Scientific Meeting (ACR/ARHP-2019)
  • 26 Apr 2019 Discontinued - Phase-II for Sjogren's syndrome in France, Sweden, United Kingdom, USA (SC) (AstraZeneca pipeline, April 2019)

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