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Dalazatide

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Drug Profile

Dalazatide

Alternative Names: Debio-0824; ShK-186

Latest Information Update: 03 Jul 2025

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At a glance

  • Originator Airmid; University of California at Irvine
  • Developer KPI Therapeutics; Seattle Childrens Research Institute; TuHURA Biosciences; University of California at Irvine; University of Groningen
  • Class Amides; Peptides; Proteins
  • Mechanism of Action Kv1.3 potassium channel inhibitors; T lymphocyte modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Autoimmune disorders; Inclusion body myositis; Inflammatory bowel diseases; Lupus nephritis; Multiple sclerosis; Obesity; Plaque psoriasis; Psoriatic arthritis; Vasculitis

Most Recent Events

  • 30 Jun 2025 Kineta has been acquired and merged into TuHURA Biosciences
  • 28 Jun 2021 No recent reports of development identified for preclinical development in Inclusion body myositis in USA (SC, Injection)
  • 28 Jul 2019 No recent reports of development identified for research development in Inflammatory-bowel-diseases in USA (SC, Injection)

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