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Research programme: metal-protein-attenuating compounds - Prana Biotechnology

Drug Profile

Research programme: metal-protein-attenuating compounds - Prana Biotechnology

Alternative Names: MPAC - Prana Biotechnology; PBT 519; PBT3 series - Prana Biotechnology; PBT4 series - Prana Biotechnology

Latest Information Update: 13 Apr 2018

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At a glance

  • Originator Prana Biotechnology
  • Class Quinazolinones
  • Mechanism of Action Alpha-synuclein inhibitors; Dopamine modulators; Iron chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Brain cancer; Parkinson's disease
  • Research Neurodegenerative disorders
  • Discontinued Age-related macular degeneration; Alzheimer's disease

Most Recent Events

  • 13 Apr 2018 Preclinical development for Parkinson's disease is ongoing in Australia (PO)
  • 21 Mar 2018 Prana Biotechnology plans a phase I trial for Parkinson's disease (In volunteers) in Australia in May 2018 (ACTRN12618000541202p)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Parkinson's-disease in Australia (PO)
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