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Research programme: metal-protein-attenuating compounds - Alterity Therapeutics

Drug Profile

Research programme: metal-protein-attenuating compounds - Alterity Therapeutics

Alternative Names: MPAC - Alterity Therapeutics; PBT 519; PBT3 series - Alterity Therapeutics; PBT4 series - Alterity Therapeutics

Latest Information Update: 28 Dec 2022

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At a glance

  • Originator Prana Biotechnology
  • Developer Alterity Therapeutics; Prana Biotechnology
  • Class Quinazolinones
  • Mechanism of Action Alpha-synuclein inhibitors; Dopamine modulators; Iron chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Age-related macular degeneration; Alzheimer's disease; Brain cancer; Neurodegenerative disorders; Parkinson's disease

Most Recent Events

  • 28 Dec 2022 Discontinued - Preclinical for Brain cancer in Australia (unspecified route)
  • 28 Dec 2022 Discontinued - Preclinical for Parkinson's disease in Australia (PO)
  • 28 Dec 2022 Discontinued for Neurodegenerative disorders in Australia (unspecified route)
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