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Research programme: esterase-sensitive motif targeted therapeutics - Macrophage Pharma

Drug Profile

Research programme: esterase-sensitive motif targeted therapeutics - Macrophage Pharma

Alternative Names: CHR 6155; ESM™-p38 MAPK inhibitor; MPL 5821

Latest Information Update: 28 Jan 2019

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At a glance

  • Originator Chroma Therapeutics
  • Developer Chroma Therapeutics; GlaxoSmithKline
  • Class Antineoplastics; Small molecules
  • Mechanism of Action DNA inhibitors; Histone deacetylase inhibitors; HSP90 heat-shock protein inhibitors; Macrophage colony stimulating factor inhibitors; P38 mitogen-activated protein kinase inhibitors; Polo-like kinase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer; Inflammation

Most Recent Events

  • 28 Jan 2019 No recent reports of development identified for preclinical development in Cancer in United Kingdom (PO)
  • 09 Nov 2017 Aquila BioMedical enters into an agreement with Macrophage Pharma to support preclinical immuno-oncology programmes
  • 11 May 2017 Macrophage Pharma plans a clinical trial for Cancer in 2019
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