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Thioureidobutyronitrile - Innovation Pharmaceuticals

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Drug Profile

Thioureidobutyronitrile - Innovation Pharmaceuticals

Alternative Names: Kevetrin™

Latest Information Update: 28 Nov 2023

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At a glance

  • Originator Cellceutix
  • Developer Innovation Pharmaceuticals; University of Texas M. D. Anderson Cancer Center
  • Class Amides; Antineoplastics; Inorganic sulfur compounds; Nitriles; Small molecules
  • Mechanism of Action Alkylating agents; Apoptosis stimulants; Caspase 3 stimulants; Poly(ADP-ribose) polymerase modulators; Retinoblastoma protein modulators; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Retinoblastoma; Pancreatic cancer; Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Ovarian cancer
  • No development reported Acute myeloid leukaemia; Breast cancer; Chronic myeloid leukaemia; Colorectal cancer; Glioblastoma; Head and neck cancer; Lung cancer; Lymphoma; Multiple myeloma; Pancreatic cancer; Prostate cancer; Renal cancer; Retinoblastoma; Solid tumours

Most Recent Events

  • 28 Nov 2023 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (PO)
  • 28 Jun 2021 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (IV)
  • 28 Jan 2021 No recent reports of development identified for preclinical development in Ovarian-cancer in USA (PO)

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