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At a glance
Originator
ARIAD Pharmaceuticals
Developer
ARIAD Pharmaceuticals; Dana-Farber Cancer Institute; Fundacion CRIS de Investigacion para Vencer el Cancer; Incyte Corporation; Massachusetts General Hospital; Mayo Clinic; National Cancer Institute (USA); Otsuka Beijing Research Institute; Otsuka Pharmaceutical; Takeda; University of Birmingham; University of Colorado at Denver
Class
Antineoplastics; Benzamides; Imidazoles; Piperazines; Pyridazines; Small molecules
Mechanism of Action
Bcr-abl tyrosine kinase inhibitors; Fibroblast growth factor receptor antagonists; Fms-like tyrosine kinase 3 inhibitors; Platelet derived growth factor alpha receptor antagonists; Proto oncogene protein c ret inhibitors; Proto oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor antagonists
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
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