Drug Profile


Alternative Names: MSC-2430913A; ONO-4641; S1P agonist - Ono Pharmaceutical

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Ono Pharmaceutical
  • Class Azetidines; Carboxylic acids; Naphthalenes; Small molecules
  • Mechanism of Action Sphingosine 1 phosphate receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Multiple sclerosis

Most Recent Events

  • 27 Dec 2014 Ono terminates a phase III trial in Multiple Sclerosis in Austria, Belgium, Estonia, Germany, Greece, Hungary, Latvia, Portugal and Spain (EudraCT2013-002351-15; EudraCT2013-003126-83)
  • 19 Jun 2014 Merck terminates its licence for ceralifimod
  • 16 Apr 2014 Phase-III clinical trials in Multiple sclerosis in Belgium (PO) (EudraCT2013-003126-83)
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