Drug Profile


Alternative Names: Glanatec; K-115; K-115-R; Ripasudil hydrocholoride hydrate

Latest Information Update: 07 Jun 2018

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At a glance

  • Originator D. Western Therapeutics Institute
  • Developer Kowa Pharmaceutical
  • Class Azepines; Eye disorder therapies; Fluorine compounds; Isoquinolines; Small molecules; Sulfonamides
  • Mechanism of Action Rho-associated kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Glaucoma; Ocular hypertension
  • Phase II Diabetic retinopathy

Most Recent Events

  • 01 Apr 2017 Kowa initiates enrolment in a clinical trial for Glaucoma in Japan (JapicCTI-173562)
  • 28 Feb 2017 Phase-II development for Diabetic retinopathy is ongoing in Japan (Ophthalmic)
  • 02 Dec 2014 Launched for Glaucoma (Combination therapy, Monotherapy) in Japan (Ophthalmic)
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