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Picropodophyllin - Axelar AB

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Drug Profile

Picropodophyllin - Axelar AB

Alternative Names: AXL-1717

Latest Information Update: 16 Sep 2020

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At a glance

  • Originator Axelar
  • Class Antineoplastics; Small molecules
  • Mechanism of Action IGF type 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • No development reported Astrocytoma; Haematological malignancies; Solid tumours

Most Recent Events

  • 16 Sep 2020 No development reported - Phase-I/II for Astrocytoma (Late-stage disease, Second-line therapy or greater) in USA (PO) (Axelar AB website, September 2020)
  • 26 Sep 2019 Cadila Pharmaceuticals plans a phase I trial for Solid tumours (Late-stage disease) in India (CTRI2019-02-017842)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Haematological-malignancies(Late-stage disease) in Sweden (PO)

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