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Hydrocortisone - Diurnal

Drug Profile

Hydrocortisone - Diurnal

Alternative Names: Alkindi; ALKINDI SPRINKLE; Chronocort; DNL-0200; EFMODY; Efmody; Hydrocortisone extended release - Diurnal; Infacort; Modified-release hydrocortisone

Latest Information Update: 17 Mar 2025

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At a glance

  • Originator Diurnal
  • Developer Diurnal; EffRx; Emerge Health; Eton Pharmaceuticals; Medison Pharma
  • Class Alcohols; Anti-inflammatories; Antiallergics; Glucocorticoids; Pregnenediones; Small molecules
  • Mechanism of Action Glucocorticoid receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Congenital adrenal hyperplasia; Adrenal insufficiency
  • New Molecular Entity No

Highest Development Phases

  • Marketed Adrenal insufficiency; Congenital adrenal hyperplasia

Most Recent Events

  • 17 Mar 2025 Launched for Congenital adrenal hyperplasia in Switzerland (PO), before March 2025 (EffRx pipeline, March 2025)
  • 01 Jun 2024 Interim efficacy data from a phase II CHAMPION trial in Adrenal insufficiency presented at the 106th Annual Meeting of the Endocrine Society (ENDO-2024)
  • 14 May 2024 Efficacy data from phase III extension study for Congenital adrenal hyperplasia released by Neurocrine Biosciences

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