Balixafortide - Polyphor

Drug Profile

Balixafortide - Polyphor

Alternative Names: POL-6326

Latest Information Update: 27 Sep 2018

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At a glance

  • Originator Polyphor
  • Class Antineoplastics; Cyclic peptides; Epitopes; Macrocyclic compounds; Peptidomimetics
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Asthma; Cancer; Coronary artery restenosis; Inflammation; Stem cell mobilisation; Wounds

Highest Development Phases

  • Phase II Myocardial infarction; Stem cell mobilisation
  • Phase I Breast cancer
  • No development reported Coronary artery restenosis; Inflammation; Solid tumours; Wounds

Most Recent Events

  • 10 Sep 2018 Polyphor plans a pivotal trial (Combination therapy, Late-stage disease) for Breast Cancer
  • 06 Sep 2018 Polyphor plans a pivotal trial in the US
  • 01 Aug 2018 Polyphor completes a phase I trial in Breast cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in Spain and USA (IV) (NCT01837095)
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