Balixafortide - Polyphor

Drug Profile

Balixafortide - Polyphor

Alternative Names: POL-6326

Latest Information Update: 08 May 2018

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At a glance

  • Originator Polyphor
  • Class Antineoplastics; Cyclic peptides; Epitopes; Peptidomimetics
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Asthma; Cancer; Coronary artery restenosis; Inflammation; Stem cell mobilisation; Wounds

Highest Development Phases

  • Phase II Myocardial infarction; Stem cell mobilisation
  • Phase I Breast cancer
  • No development reported Coronary artery restenosis; Inflammation; Solid tumours; Wounds

Most Recent Events

  • 03 May 2018 Polyphor plans a pivotal trial for Breast cancer (Metastatic disease; Second-line therapy or greater) in USA
  • 19 Apr 2018 Balixafortide - Polyphor receives Fast Track designation for Breast cancer [IV,Infusion] (Combination therapy, Metastatic disease, Second-line therapy or greater) in USA
  • 15 Feb 2018 Phase I development is ongoing in Breast cancer (Combination therapy, Metastatic disease, Second-line therapy or greater)
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