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Alunacedase alfa - Apeiron Biologics

Drug Profile

Alunacedase alfa - Apeiron Biologics

Alternative Names: APN-01; GSK-2586881; Recombinant-human-soluble-angiotensin-converting-enzyme-2-Apeiron-Biologics; rhACE2; rhACE2-Apeiron-Biologics

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Apeiron Biologics
  • Developer Apeiron Biologics; GlaxoSmithKline; University of British Columbia
  • Class Anti-ischaemics; Antihypertensives; Antineoplastics; Antivirals; Cardiovascular therapies; Heart failure therapies; Recombinant proteins
  • Mechanism of Action ACE stimulants; Virus internalisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Acute lung injury; Adult respiratory distress syndrome; COVID 2019 infections; Pulmonary arterial hypertension
  • Discontinued Cancer; Diabetic nephropathies; Heart failure; Hypertension; Myocardial infarction

Most Recent Events

  • 03 Nov 2022 Alunacedase alfa - Apeiron Biologics is available for licensing as of 03 Nov 2022. https://www.invios.com/
  • 03 Nov 2022 Adverse events and pharmacodynamics data from a phase I trial in COVID-2019 infections (In volunteers) released by APEIRON Respiratory Therapies
  • 27 May 2022 Apeiron Biologics completes a phase I trial in COVID-2019 infections (In volunteers) in Austria (Inhalation) (NCT05065645)
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