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Brilacidin - Innovation Pharmaceuticals

Drug Profile

Brilacidin - Innovation Pharmaceuticals

Alternative Names: Brilacidin tetrahydrochloride; Brilacidin-Ocular; Brilacidin-OM; Brilacidin-Otic; Defensin-mimetic - Innovation Pharmaceuticals; HDP-mimic - Innovation Pharmaceuticals; Host defense protein-mimic - Innovation Pharmaceuticals; PMX-30063

Latest Information Update: 28 Nov 2019

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At a glance

  • Originator PolyMedix
  • Developer Innovation Pharmaceuticals
  • Class Amides; Anti-inflammatories; Antibacterials; Guanidines; Peptidomimetics; Pyrimidines; Pyrrolidines; Small molecules
  • Mechanism of Action Cell membrane permeability enhancers; Cell membrane structure modulators; Immunomodulators; Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Stomatitis

Highest Development Phases

  • Phase II Skin and soft tissue infections; Stomatitis; Ulcerative proctitis
  • Preclinical Acne; Atopic dermatitis; Hidradenitis suppurativa; Inflammatory bowel diseases; Ulcerative colitis
  • No development reported Diabetic foot ulcer; Otitis; Wounds
  • Discontinued Intestinal infections; Ophthalmic infections

Most Recent Events

  • 25 Nov 2019 The US FDA waives Paediatric Investigation Plan for Stomatitis in patients with Head and neck cancer
  • 13 Nov 2019 Brilacidin is available for licensing for Stomatitis (Prevention) as of 13 Nov 2019. www.ipharminc.com
  • 03 Oct 2019 Innovation Pharmaceuticals plans a phase III trial for Stomatitis (In volunteers) in December 2019 (Topical, Liquid)
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