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Solithromycin - Melinta Therapeutics

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Drug Profile

Solithromycin - Melinta Therapeutics

Alternative Names: CEM-101; OP-1068; T-4288

Latest Information Update: 28 Aug 2022

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At a glance

  • Originator Optimer Pharmaceuticals
  • Developer Cempra Pharmaceuticals; FUJIFILM Toyama Chemical; Melinta Therapeutics; Toyama Chemical
  • Class Anti-infectives; Anti-inflammatories; Antibacterials; Antibronchitics; Antimalarials; Eye disorder therapies; Hepatoprotectants; Heterocyclic bicyclo compounds; Ketolides; Macrolides; Oxazoles; Pyrans; Small molecules
  • Mechanism of Action Protein 50S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Community-acquired pneumonia; Otorhinolaryngological infections
  • Phase III Bronchitis; Chlamydial infections; Gonorrhoea; Respiratory tract infections; Sinusitis; Urethritis
  • Phase II Chronic obstructive pulmonary disease; Non-alcoholic steatohepatitis
  • No development reported Anthrax; Bacterial infections; Enterococcal infections; Eye disorders; Legionella infections; Malaria; Methicillin-resistant Staphylococcus aureus infections; Mycobacterium avium complex infections; Mycoplasma infections; Obstetric and gynaecological infections; Otitis media; Tularaemia

Most Recent Events

  • 28 Aug 2022 No recent reports of development identified for preclinical development in Eye-disorders in USA (Ophthalmic)
  • 25 Apr 2019 Preregistration for Otorhinolaryngological infections in Japan (PO)
  • 28 Oct 2018 No recent reports of development identified for phase-I development in Community-acquired-pneumonia(In volunteers) in Japan (PO, Tablet)

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