Asfotase alfa - Alexion Pharmaceuticals

Drug Profile

Asfotase alfa - Alexion Pharmaceuticals

Alternative Names: ALXN1215; Asfotase alpha; ENB-0040; Strensiq

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Enobia Pharma
  • Developer Alexion Pharmaceuticals
  • Class Recombinant fusion proteins
  • Mechanism of Action Alkaline phosphatase stimulants; Esterase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypophosphatasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypophosphatasia
  • Preclinical Neurofibromatoses

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 17 Mar 2018 Final efficacy and adverse events data from a long term extension trial in Hypophosphatasia (paediatric onset hypophosphatasia) presented at the 100th Annual Meeting of the Endocrine Society (ENDO-2018)
  • 17 Mar 2018 Pharmacodynamics and adverse events data from a phase IIa trial in Hypophosphatasia (paediatric-onset hyperphosphataemia) presented at the the 100th Annual Meeting of the Endocrine Society (ENDO-2018)
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