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Asfotase alfa - Alexion AstraZeneca Rare Disease

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Drug Profile

Asfotase alfa - Alexion AstraZeneca Rare Disease

Alternative Names: ALXN1215; Asfotase alpha; ENB-0040; Strensiq

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Enobia Pharma
  • Developer Alexion AstraZeneca Rare Disease
  • Class Antineoplastics; Recombinant fusion proteins
  • Mechanism of Action Alkaline phosphatase stimulants; Esterase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypophosphatasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypophosphatasia
  • Discontinued Neurofibromatosis 1

Most Recent Events

  • 28 Dec 2022 Discontinued - Phase-II/III for Hypophosphatasia (In children, In infants) in France (SC)(Alexion Pharmaceuticals Pipeline, December 2022)
  • 28 Dec 2022 Discontinued - Phase-II/III for Hypophosphatasia (In children, In infants) in Russia (SC)(Alexion Pharmaceuticals Pipeline, December 2022)
  • 28 Dec 2022 Discontinued - Phase-II/III for Hypophosphatasia (In children, In infants) in Saudi Arabia (SC)(Alexion Pharmaceuticals Pipeline, December 2022)

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