Ficlatuzumab - AVEO Oncology

Drug Profile

Ficlatuzumab - AVEO Oncology

Alternative Names: AV-299; Ficla; SCH-900105

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator AVEO Pharmaceuticals
  • Developer AVEO Oncology; AVEO Pharmaceuticals; Dana-Farber Cancer Institute; University of Arizona Cancer Center; University of California at San Francisco; University of Pittsburgh
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Hepatocyte growth factor inhibitors; Proto oncogene protein c met inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Head and neck cancer; Non-small cell lung cancer
  • Phase I Acute myeloid leukaemia; Pancreatic cancer
  • No development reported Lymphoma; Multiple myeloma; Solid tumours
  • Discontinued Glioblastoma

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 12 Dec 2017 Ficlatuzumab- AVEO Oncology is available for licensing as of 07 Dec 2017.
  • 07 Dec 2017 Phase-I clinical trials in Pancreatic cancer (First-line therapy, Combination therapy, Late-stage disease, Metastatic disease) in USA (IV) (NCT03316599)
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