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Peficitinib - Astellas Pharma

Drug Profile

Peficitinib - Astellas Pharma

Alternative Names: ASP-015K; ASP-015K hydrobromide; JNJ-54781532; Peficitinib hydrobromide; Smyraf

Latest Information Update: 01 Nov 2019

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At a glance

  • Originator Astellas Pharma
  • Class Adamantanes; Amides; Anti-inflammatories; Antipsoriatics; Antirheumatics; Pyridines; Pyrroles; Small molecules
  • Mechanism of Action Immunosuppressants; Janus kinase 1 inhibitors; Janus kinase 3 inhibitors; Janus kinase-2 inhibitors; TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Rheumatoid arthritis
  • Discontinued Plaque psoriasis; Transplant rejection; Ulcerative colitis

Most Recent Events

  • 31 Oct 2019 Astellas Pharma plans a phase I trial for Healthy volunteers in China (PO) in October 2019 (NCT04143477)
  • 10 Jul 2019 Launched for Rheumatoid arthritis in Japan (PO)
  • 12 Jun 2019 Safety, efficacy and pharmacokinetics data from a phase I trial in Healthy volunteers and impaired Renal functional presented at the 20th Annual Congress of the European League Against Rheumatism (EULAR-2019)
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