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Tradipitant - Vanda Pharmaceuticals

Drug Profile

Tradipitant - Vanda Pharmaceuticals

Alternative Names: LY-686017; VLY 686

Latest Information Update: 22 May 2024

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At a glance

  • Originator Eli Lilly and Company
  • Developer Eli Lilly and Company; National Institute on Alcohol Abuse and Alcoholism; Vanda Pharmaceuticals
  • Class Anti-inflammatories; Antipruritics; Antivirals; Anxiolytics; Behavioural disorder therapies; Chlorobenzenes; Gastrokinetics; Pyridines; Skin disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Neurokinin 1 receptor antagonists; Substance P inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Gastroparesis
  • Phase III Atopic dermatitis; COVID 2019 infections; Motion sickness
  • Phase II Dyspepsia; Pruritus
  • Discontinued Alcoholism; Social phobia

Most Recent Events

  • 15 May 2024 Efficacy data from the phase III Motion Serifos trial in Motion sickness released by Vanda Pharmaceuticals
  • 08 May 2024 Vanda Pharmaceuticals announces intention to file an NDA with the US FDA for Motion sickness in 2024
  • 04 Dec 2023 Preregistration for Gastroparesis in USA (PO)
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