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OMS 527

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Drug Profile

OMS 527

Alternative Names: OMS-182399; OMS527; PDE7 inhibitor - Omeros; Type 7 cyclic nucleotide phosphodiesterase inhibitor - Omeros

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Asubio Pharma
  • Developer National Institute of Drug Abuse; Omeros Corporation; The Parkinsons Institute and Clinical Center
  • Class Antiparkinsonians; Drug withdrawal therapies; Small molecules
  • Mechanism of Action Type 7 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cocaine-related disorders
  • Phase Unknown Dyskinesias
  • No development reported Impulse control disorders; Movement disorders

Most Recent Events

  • 13 Mar 2025 Phase-I clinical trials in Cocaine-related disorders (PO) before March 2025
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Impulse-control-disorders in USA (PO)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Movement-disorders in USA (PO)

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