Lesinurad - AstraZeneca

Drug Profile

Lesinurad - AstraZeneca

Alternative Names: RDEA-594; RDEA594 sodium; Zurampic

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Ardea Biosciences
  • Developer Ardea Biosciences; Ironwood Pharmaceuticals
  • Class Acetic acids; Antigouts; Cyclopropanes; Naphthalenes; Small molecules; Sulfides; Triazoles; Uricosurics
  • Mechanism of Action SLC22A12 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gout

Most Recent Events

  • 22 Feb 2017 Ironwood Pharmaceuticals has patent protection for lesinurad in USA (Ironwood Pharmaceuticals 10-K, February 2017)
  • 22 Feb 2017 Ironwood Pharmaceuticals has patents pending for lesinurad in USA (Ironwood Pharmaceuticals 10-K, February 2017)
  • 11 Nov 2016 Pooled efficacy and adverse events data from phase III Long-term extension studies for the CLEAR and CRYSTAL trials in Gout presented at the 80th American College of Rheumatology and the 51st Annual Meeting of the Association of Rheumatology and Health Professionals (ACR-ARHP-2016)
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