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PF 4236921

Drug Profile

PF 4236921

Alternative Names: PF-04236921; PF-4236921

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator Pfizer
  • Class Anti-inflammatories; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Interleukin 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Crohn's disease
  • Discontinued Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 01 Mar 2016 Pfizer completes the ANDANTE II trial for Crohn's disease in USA, Canada, Brazil, the UK, Austria, Belgium, Czech Republic, Denmark, France, Germany, Greece, Hungary, Ireland, Italy, Sweden, Switzerland, Australia, New Zealand and Israel (NCT01345318)
  • 28 Oct 2015 Discontinued - Phase-II for Systemic lupus erythematosus in USA, Romania, Puerto Rico, Poland, Peru, Moldova, South Korea, Colombia, Chile, Argentina, Taiwan, Germany and Hungary (SC)
  • 17 Jun 2015 Phase-II development is ongoing for Crohn's disease and Systemic lupus erythematosus in World
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