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Elobixibat - Albireo Pharma/EA Pharma

Drug Profile

Elobixibat - Albireo Pharma/EA Pharma

Alternative Names: A-3309; AJG-533; Goofice

Latest Information Update: 15 Jul 2019

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At a glance

  • Originator AstraZeneca
  • Developer Albireo Pharma; EA Pharma; Mochida Pharmaceutical
  • Class 2 ring heterocyclic compounds; Amides; Carboxylic acids; Hepatoprotectants; Laxatives; Small molecules; Sulfides; Sulfones; Thiazepines
  • Mechanism of Action Sodium-bile acid cotransporter inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Constipation
  • Phase II Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
  • Discontinued Dyslipidaemias; Irritable bowel syndrome

Most Recent Events

  • 11 Apr 2019 Albireo Pharma plans a phase II trial for Non-alcoholic steatohepatitis and Non-alcoholic fatty liver disease in the second quarter of 2019
  • 11 Apr 2019 US FDA approves IND application for elobixibat in Non-alcoholic fatty liver disease and Non-alcoholic steatohepatitis
  • 07 Aug 2018 Albireo Pharma has patent protection for elobixibat in USA and Europe
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